منابع مشابه
Caspase-dependent apoptosis in light-induced retinal degeneration.
PURPOSE To study the apoptotic mechanism involved in our model of light-induced retinal degeneration. METHODS Rats were injected intravitreally with PBS, 2% dimethyl sulfoxide (DMSO), caspase inhibitor Z-VAD-FMK (1.06 mM), Z-YVAD-FMK (0.16 mM), or Z-DEVD-FMK (2 mM) before they were placed in constant light (3400 lux) for 24 hours. Additional controls included rats that were uninjected or were...
متن کاملP-35: Vitrification Induced Apoptosis in MiceBlastocysts
Background: Apoptosis is induced by several factors and has an important role in embryonic development. Since vitrification-induced embryonic damages could be resulted from an increase in apoptosis occurrence,the aim of the present study is to investigate the effect of vitrification on induction of apoptosis in blastocysts. Materials and Methods: For this purpose 20 balb-c mice superovulated an...
متن کاملOleuropein Attenuates Deltamethrin-induced Apoptosis in Rat Cerebellar Purkinje Neurons
Background: Deltamethrin (DM) is a synthetic pyrethroid insecticide that can elicit neurotoxicity, and lead to apoptosis. There is accumulating evidence that oleuropein (OE) has anti-apoptotic effect. This study aimed at determining the DM toxicity and anti-apoptotic effect of OE pretreatment in cerebellar Purkinje neurons. Materials and Methods: Rats were randomly divided into four groups a...
متن کاملThe tumor suppressor p53 can both stimulate and inhibit ultraviolet light-induced apoptosis.
We have previously shown that the tumor suppressor p53 can play a protective role against UV-induced apoptosis in human fibroblasts. In the present study, we investigated whether the protective function of p53 expression is established before or after UV irradiation. Using a stable human cell line expressing a murine temperature-sensitive p53 in which p53 function could be tightly and reversibl...
متن کاملBright cyclic rearing protects albino mouse retina against acute light-induced apoptosis.
PURPOSE Previous studies have shown that albino rats born and raised in bright cyclic light are protected from light-induced apoptosis. The present study was designed to determine if bright cyclic rearing provides protection against retinal degeneration caused by acute light exposure in albino mice. METHODS BALB/c mice were born in dim cyclic light (5 lux, 12 h ON/OFF). At 1 week of age, half...
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ژورنال
عنوان ژورنال: Genome Biology
سال: 2001
ISSN: 1465-6906
DOI: 10.1186/gb-spotlight-20011105-01